Brucellome hépatique: deux nouveaux cas et revue de la littérature [Hepatic brucelloma: 2 cases and a review of the literature].

Détails

ID Serval
serval:BIB_F3E918CB3271
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Titre
Brucellome hépatique: deux nouveaux cas et revue de la littérature [Hepatic brucelloma: 2 cases and a review of the literature].
Périodique
Gastroentérologie Clinique et Biologique
Auteur⸱e⸱s
Halimi C., Bringard N., Boyer N., Vilgrain V., Panis Y., Degott C., Brouland J.P., Boudiaf M., Valleur P., Henry-Biabaud E., Valla D.
ISSN
0399-8320 (Print)
ISSN-L
0399-8320
Statut éditorial
Publié
Date de publication
1999
Peer-reviewed
Oui
Volume
23
Numéro
4
Pages
513-517
Langue
français
Notes
Publication types: Case Reports
Résumé
We report two new cases of hepatic brucelloma in addition to the 22 previously reported cases in the literature. Our analysis of these cases reveals certain characteristics. Hepatic brucelloma is a rare localization that follows previously undetected acute brucellosis. Brucelloma is a result of caseification of a granulomatous reaction induced by persistent Brucella in macrophages. Clinical manifestations can mimic malignant liver tumors or pyogenic, amebic liver abscess. Diagnosis is based on the association of characteristic imaging features (central calcification and peripheral necrotic areas), positive serology and hepatic granulomas. Brucella is rarely isolated in the blood or liver. Awareness of this clinical variant can prevent unnecessary laparotomy. Treatment should begin with rifampicine (900 mg per day) and doxycyclin (200 mg per day) for 3 months. If medical treatment is unsuccessful, percutaneous or surgical drainage should be performed. A cure should be achieved in all cases.
Mots-clé
Anti-Bacterial Agents/therapeutic use, Brucellosis/diagnosis, Brucellosis/drug therapy, Diagnosis, Differential, Doxycycline/therapeutic use, Granuloma/diagnosis, Granuloma/microbiology, Humans, Liver Diseases/diagnosis, Liver Diseases/microbiology, Macrophages/microbiology, Male, Middle Aged, Rifampin/therapeutic use
Pubmed
Web of science
Création de la notice
13/10/2015 9:28
Dernière modification de la notice
20/08/2019 16:20
Données d'usage