Brucellome hépatique: deux nouveaux cas et revue de la littérature [Hepatic brucelloma: 2 cases and a review of the literature].

Details

Serval ID
serval:BIB_F3E918CB3271
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Title
Brucellome hépatique: deux nouveaux cas et revue de la littérature [Hepatic brucelloma: 2 cases and a review of the literature].
Journal
Gastroentérologie Clinique et Biologique
Author(s)
Halimi C., Bringard N., Boyer N., Vilgrain V., Panis Y., Degott C., Brouland J.P., Boudiaf M., Valleur P., Henry-Biabaud E., Valla D.
ISSN
0399-8320 (Print)
ISSN-L
0399-8320
Publication state
Published
Issued date
1999
Peer-reviewed
Oui
Volume
23
Number
4
Pages
513-517
Language
french
Notes
Publication types: Case Reports
Abstract
We report two new cases of hepatic brucelloma in addition to the 22 previously reported cases in the literature. Our analysis of these cases reveals certain characteristics. Hepatic brucelloma is a rare localization that follows previously undetected acute brucellosis. Brucelloma is a result of caseification of a granulomatous reaction induced by persistent Brucella in macrophages. Clinical manifestations can mimic malignant liver tumors or pyogenic, amebic liver abscess. Diagnosis is based on the association of characteristic imaging features (central calcification and peripheral necrotic areas), positive serology and hepatic granulomas. Brucella is rarely isolated in the blood or liver. Awareness of this clinical variant can prevent unnecessary laparotomy. Treatment should begin with rifampicine (900 mg per day) and doxycyclin (200 mg per day) for 3 months. If medical treatment is unsuccessful, percutaneous or surgical drainage should be performed. A cure should be achieved in all cases.
Keywords
Anti-Bacterial Agents/therapeutic use, Brucellosis/diagnosis, Brucellosis/drug therapy, Diagnosis, Differential, Doxycycline/therapeutic use, Granuloma/diagnosis, Granuloma/microbiology, Humans, Liver Diseases/diagnosis, Liver Diseases/microbiology, Macrophages/microbiology, Male, Middle Aged, Rifampin/therapeutic use
Pubmed
Web of science
Create date
13/10/2015 9:28
Last modification date
20/08/2019 16:20
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