Venous thromboembolism in critically Ill patients with COVID-19: Results of a screening study for deep vein thrombosis.

Détails

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Etat: Public
Version: Final published version
Licence: CC BY-NC-ND 4.0
ID Serval
serval:BIB_F213C2D7C2EC
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Venous thromboembolism in critically Ill patients with COVID-19: Results of a screening study for deep vein thrombosis.
Périodique
Research and practice in thrombosis and haemostasis
Auteur(s)
Longchamp A., Longchamp J., Manzocchi-Besson S., Whiting L., Haller C., Jeanneret S., Godio M., Garcia Martinez J.J., Bonjour T., Caillat M., Maitre G., Thaler J.M., Pantet R., Donner V., Dumoulin A., Emonet S., Greub G., Friolet R., Robert-Ebadi H., Righini M., Sanchez B., Delaloye J.
ISSN
2475-0379 (Electronic)
ISSN-L
2475-0379
Statut éditorial
Publié
Date de publication
07/2020
Peer-reviewed
Oui
Volume
4
Numéro
5
Pages
842-847
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: epublish
Résumé
The rapid spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and coronavirus disease 2019 (COVID-19), has caused more than 3.9 million cases worldwide. Currently, there is great interest to assess venous thrombosis prevalence, diagnosis, prevention, and management in patients with COVID-19.
To determine the prevalence of venous thromboembolism (VTE) in critically ill patients with COVID-19, using lower limbs venous ultrasonography screening.
Beginning March 8, we enrolled 25 patients who were admitted to the intensive care unit (ICU) with confirmed SARS-CoV-2 infections. The presence of lower extremity deep vein thrombosis (DVT) was systematically assessed by ultrasonography between day 5 and 10 after admission. The data reported here are those available up to May 9, 2020.
The mean (± standard deviation) age of the patients was 68 ± 11 years, and 64% were men. No patients had a history of VTE. During the ICU stay, 8 patients (32%) had a VTE; 6 (24%) a proximal DVT, and 5 (20%) a pulmonary embolism. The rate of symptomatic VTE was 24%, while 8% of patients had screen-detected DVT. Only those patients with a documented VTE received a therapeutic anticoagulant regimen. As of May 9, 2020, 5 patients had died (20%), 2 remained in the ICU (8%), and 18 were discharged (72%).
In critically ill patients with SARS-CoV-2 infections, DVT screening at days 5-10 of admission yielded a 32% prevalence of VTE. Seventy-five percent of events occurred before screening. Earlier screening might be effective in optimizing care in ICU patients with COVID-19.
Mots-clé
COVID‐19, SARS virus, pulmonary embolism, ultrasonography, venous thrombosis
Pubmed
Web of science
Open Access
Oui
Financement(s)
Fonds national suisse / Carrières / PZ00P3-185927
Création de la notice
24/07/2020 14:12
Dernière modification de la notice
30/04/2021 7:16
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