Performance du frottis nasopharyngé-PCR pour le diagnostic du Covid-19 - Recommandations pratiques sur la base des premières données scientifiques [Covid-19 diagnosis : clinical recommendations and performance of nasopharyngeal swab-PCR]

Détails

Ressource 1Télécharger: RMS_689_699.pdf (22018.39 [Ko])
Etat: Public
Version: Final published version
Licence: CC BY-NC-ND 4.0
ID Serval
serval:BIB_F0C317F7B520
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Performance du frottis nasopharyngé-PCR pour le diagnostic du Covid-19 - Recommandations pratiques sur la base des premières données scientifiques [Covid-19 diagnosis : clinical recommendations and performance of nasopharyngeal swab-PCR]
Périodique
Revue medicale suisse
Auteur⸱e⸱s
Kokkinakis I., Selby K., Favrat B., Genton B., Cornuz J.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Statut éditorial
Publié
Date de publication
08/04/2020
Peer-reviewed
Oui
Volume
16
Numéro
689
Pages
699-701
Langue
français
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Résumé
The Covid-19 pandemic imposes new diagnostic strategies in order to optimize the medical care of our patients. The current biblio-graphy, although of low quality, shows a sensitivity of 56 to 83 % for the Covid-19 PCR. Even though one negative test can exclude a Covid-19 in the majority of cases, the NPV (Negative Predictive Value) decreases with increasing prevalence (pre-test probability). This finding suggests the need for strict auto-isolation of patients until the resolution of their symptoms. For patients that present with typical symptoms, who have a presumed Covid-19 prevalence of -40-50 %, a negative test should be interpreted with caution and a repeat test may be needed.
Mots-clé
Betacoronavirus/isolation & purification, Coronavirus Infections/diagnosis, Humans, Pandemics, Pneumonia, Viral/diagnosis, Polymerase Chain Reaction/methods, Polymerase Chain Reaction/standards, Predictive Value of Tests, Sensitivity and Specificity
Pubmed
Création de la notice
14/04/2020 10:37
Dernière modification de la notice
21/11/2022 8:30
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