Patients' sibling history was sensitive for hypertension and specific for diabetes.

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Etat: Public
Version: de l'auteur⸱e
ID Serval
serval:BIB_EFD7DD0802C1
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Patients' sibling history was sensitive for hypertension and specific for diabetes.
Périodique
Journal of clinical epidemiology
Auteur⸱e⸱s
Bochud M., Burnier M., Paccaud F., Falconnet C., Mooser V., Both N., Bovet P.
ISSN
0895-4356
ISSN-L
0895-4356
Statut éditorial
Publié
Date de publication
2004
Peer-reviewed
Oui
Volume
57
Numéro
5
Pages
497-501
Langue
anglais
Résumé
OBJECTIVE: We examined the analytic validity of reported family history of hypertension and diabetes among siblings in the Seychelles. STUDY DESIGN AND SETTING: Four hundred four siblings from 73 families with at least two hypertensive persons were identified through a national hypertension register. Two gold standards were used prospectively. Sensitivity was the proportion of respondents who indicated the presence of disease in a sibling, given that the sibling reported to be affected (personal history gold standard) or was clinically affected (clinical status gold standard). Specificity was the proportion of respondents who reported an unaffected sibling, given that the sibling reported to be unaffected or was clinically unaffected. Respondents gave information on the disease status in their siblings in approximately two-thirds of instances. RESULTS: When sibling history could be obtained (n=348 for hypertension, n=404 for diabetes), the sensitivity and the specificity of the sibling history were, respectively, 90 and 55% for hypertension, and 61 and 98% for diabetes, using clinical status and, respectively, 89 and 78% for hypertension, and 53 and 98% for diabetes, using personal history. CONCLUSION: The sibling history, when available, is a useful screening test to detect hypertension, but it is less useful to detect diabetes.
Mots-clé
Adult, Aged, Diabetes Mellitus, Female, Genetic Predisposition to Disease, Humans, Hypertension, Male, Mass Screening, Medical History Taking, Middle Aged, Prospective Studies, Sensitivity and Specificity, Seychelles
Pubmed
Web of science
Création de la notice
14/03/2008 11:20
Dernière modification de la notice
20/08/2019 17:17
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