Potential role of stereotactic linac based radiotherapy using micromulti leaf collimator in the treatment of bilateral retinoblastomas
Détails
ID Serval
serval:BIB_ECE520851B5C
Type
Actes de conférence (partie): contribution originale à la littérature scientifique, publiée à l'occasion de conférences scientifiques, dans un ouvrage de compte-rendu (proceedings), ou dans l'édition spéciale d'un journal reconnu (conference proceedings).
Sous-type
Abstract (résumé de présentation): article court qui reprend les éléments essentiels présentés à l'occasion d'une conférence scientifique dans un poster ou lors d'une intervention orale.
Collection
Publications
Institution
Titre
Potential role of stereotactic linac based radiotherapy using micromulti leaf collimator in the treatment of bilateral retinoblastomas
Titre de la conférence
8th Annual Meeting of the Scientific Association of Swiss Radiation Oncology (SASRO)
Adresse
Lucerne, Switzerland, March 11-13, 2004
ISBN
0179-7158
Statut éditorial
Publié
Date de publication
2004
Peer-reviewed
Oui
Volume
180
Série
Strahlentherapie und Onkologie
Pages
103
Langue
anglais
Notes
Document Type: Meeting Abstract
Résumé
Objective: To assess the potential role of improved dose distribution with stereotactic radiotherapy (SRT) compared to conventional
radiation therapy (RT) on the incidence of treatment induced secondary cancers in retinoblastomas
Material and Methods: Five children were used as models for the purpose of this study. A comparative dosimetric study is presented in
which a four or five field stereotactic 6MV x ray plan is compared with a one D shaped field conventional RT 6MV
x ray plan.. The gross tumor volume encompasses all known gross disease. For the unfavorable patients the clinical
target volume includes the entire retina and vitreous and spares the anterior segment of the eye. A prescribed
dose of 45 Gy at 1.8 Gy par fraction was used. Dose volume histograms (DVHs) of the lens, lacrimal gland, bony
orbit, soft tissues and brain parenchyma were compared.
Results: The non coplanar approach result in a limited exposure of bony volume (dose delivered to 50% of the volume: 5-6
Gy), and soft tissue volume. No dose was delivered to controlateral eye, chiasma, frontal or temporal lobes, pituitary
gland
Conclusion: SRT may help to reduce the irradiation of normal brain, soft tissue and bony orbit that is responsible of second
malignancy and functional long term complications in children with retinoblastoma.
radiation therapy (RT) on the incidence of treatment induced secondary cancers in retinoblastomas
Material and Methods: Five children were used as models for the purpose of this study. A comparative dosimetric study is presented in
which a four or five field stereotactic 6MV x ray plan is compared with a one D shaped field conventional RT 6MV
x ray plan.. The gross tumor volume encompasses all known gross disease. For the unfavorable patients the clinical
target volume includes the entire retina and vitreous and spares the anterior segment of the eye. A prescribed
dose of 45 Gy at 1.8 Gy par fraction was used. Dose volume histograms (DVHs) of the lens, lacrimal gland, bony
orbit, soft tissues and brain parenchyma were compared.
Results: The non coplanar approach result in a limited exposure of bony volume (dose delivered to 50% of the volume: 5-6
Gy), and soft tissue volume. No dose was delivered to controlateral eye, chiasma, frontal or temporal lobes, pituitary
gland
Conclusion: SRT may help to reduce the irradiation of normal brain, soft tissue and bony orbit that is responsible of second
malignancy and functional long term complications in children with retinoblastoma.
Web of science
Création de la notice
28/04/2008 11:35
Dernière modification de la notice
20/08/2019 17:14
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