Potential role of stereotactic linac based radiotherapy using micromulti leaf collimator in the treatment of bilateral retinoblastomas
Details
Serval ID
serval:BIB_ECE520851B5C
Type
Inproceedings: an article in a conference proceedings.
Publication sub-type
Abstract (Abstract): shot summary in a article that contain essentials elements presented during a scientific conference, lecture or from a poster.
Collection
Publications
Institution
Title
Potential role of stereotactic linac based radiotherapy using micromulti leaf collimator in the treatment of bilateral retinoblastomas
Title of the conference
8th Annual Meeting of the Scientific Association of Swiss Radiation Oncology (SASRO)
Address
Lucerne, Switzerland, March 11-13, 2004
ISBN
0179-7158
Publication state
Published
Issued date
2004
Peer-reviewed
Oui
Volume
180
Series
Strahlentherapie und Onkologie
Pages
103
Language
english
Notes
Document Type: Meeting Abstract
Abstract
Objective: To assess the potential role of improved dose distribution with stereotactic radiotherapy (SRT) compared to conventional
radiation therapy (RT) on the incidence of treatment induced secondary cancers in retinoblastomas
Material and Methods: Five children were used as models for the purpose of this study. A comparative dosimetric study is presented in
which a four or five field stereotactic 6MV x ray plan is compared with a one D shaped field conventional RT 6MV
x ray plan.. The gross tumor volume encompasses all known gross disease. For the unfavorable patients the clinical
target volume includes the entire retina and vitreous and spares the anterior segment of the eye. A prescribed
dose of 45 Gy at 1.8 Gy par fraction was used. Dose volume histograms (DVHs) of the lens, lacrimal gland, bony
orbit, soft tissues and brain parenchyma were compared.
Results: The non coplanar approach result in a limited exposure of bony volume (dose delivered to 50% of the volume: 5-6
Gy), and soft tissue volume. No dose was delivered to controlateral eye, chiasma, frontal or temporal lobes, pituitary
gland
Conclusion: SRT may help to reduce the irradiation of normal brain, soft tissue and bony orbit that is responsible of second
malignancy and functional long term complications in children with retinoblastoma.
radiation therapy (RT) on the incidence of treatment induced secondary cancers in retinoblastomas
Material and Methods: Five children were used as models for the purpose of this study. A comparative dosimetric study is presented in
which a four or five field stereotactic 6MV x ray plan is compared with a one D shaped field conventional RT 6MV
x ray plan.. The gross tumor volume encompasses all known gross disease. For the unfavorable patients the clinical
target volume includes the entire retina and vitreous and spares the anterior segment of the eye. A prescribed
dose of 45 Gy at 1.8 Gy par fraction was used. Dose volume histograms (DVHs) of the lens, lacrimal gland, bony
orbit, soft tissues and brain parenchyma were compared.
Results: The non coplanar approach result in a limited exposure of bony volume (dose delivered to 50% of the volume: 5-6
Gy), and soft tissue volume. No dose was delivered to controlateral eye, chiasma, frontal or temporal lobes, pituitary
gland
Conclusion: SRT may help to reduce the irradiation of normal brain, soft tissue and bony orbit that is responsible of second
malignancy and functional long term complications in children with retinoblastoma.
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28/04/2008 11:35
Last modification date
20/08/2019 17:14
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