How Donor Profile Affects the Outcome of Heart Transplant: A New Score to Predict Primary Graft Failure

Détails

ID Serval
serval:BIB_E89410DC02D1
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
How Donor Profile Affects the Outcome of Heart Transplant: A New Score to Predict Primary Graft Failure
Périodique
Journal of Thoracic Disease and Cardiothoracic Surgery
Auteur⸱e⸱s
Hoti E., Hullin R., Kirsch M., Schütz F., Tozzi P.
ISSN
2693-2156
Statut éditorial
Publié
Date de publication
21/11/2023
Peer-reviewed
Oui
Volume
4
Numéro
5
Pages
01-11
Langue
anglais
Résumé
Aim: This study aimed to identify demographic and clinical parameters in donors that could predict the ischaemic time
tolerated by the heart transplant in order to increase the number of heart transplantation performed in our centre by
expanding the area of graft recruitment.
Methods: A single site retrospective study was conducted on 116 heart transplantations performed in our centre between
2013 and 2021. Multivariate logistic regression analyses were used to identify interactions between the different donor
parameters.
Results: Sex, weight, height, total graft ischemic time were the donor parameters independently correlated with primary
graft failure (p < 0.1). The logistic regression model included 11 variables, with an AUC of 0.81, this model appears to
perform well in the prediction of primary graft failure in the recipient.
Conclusions: A predictive score of primary graft failure was created based on identified donors parameters that may help
identify grafts with a higher tolerance to ischemia.
Mots-clé
Heart transplantation, organ donor, primary graft failure, data base analysis
Open Access
Oui
Création de la notice
28/05/2024 16:18
Dernière modification de la notice
25/07/2024 5:56
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