Recording and reporting of ultra-high dose rate "FLASH" delivery for preclinical and clinical settings.

Détails

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Accès restreint UNIL
Etat: Public
Version: de l'auteur⸱e
Licence: Non spécifiée
ID Serval
serval:BIB_E03324B6E50A
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Recording and reporting of ultra-high dose rate "FLASH" delivery for preclinical and clinical settings.
Périodique
Radiotherapy and oncology
Auteur⸱e⸱s
Tobias Böhlen T., Psoroulas S., Aylward J.D., Beddar S., Douralis A., Delpon G., Garibaldi C., Gasparini A., Schüler E., Stephan F., Moeckli R., Subiel A.
ISSN
1879-0887 (Electronic)
ISSN-L
0167-8140
Statut éditorial
Publié
Date de publication
11/2024
Peer-reviewed
Oui
Volume
200
Pages
110507
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Résumé
Treatments at ultra-high dose rate (UHDR) have the potential to improve the therapeutic index of radiation therapy (RT) by sparing normal tissues compared to conventional dose rate irradiations. Insufficient and inconsistent reporting in physics and dosimetry of preclinical and translational studies may have contributed to a reproducibility crisis of radiobiological data in the field. Consequently, the development of a common terminology, as well as common recording, reporting, dosimetry, and metrology standards is required. In the context of UHDR irradiations, the temporal dose delivery parameters are of importance, and under-reporting of these parameters is also a concern.This work proposes a standardization of terminology, recording, and reporting to enhance comparability of both preclinical and clinical UHDR studies and and to allow retrospective analyses to aid the understanding of the conditions which give rise to the FLASH effect.
Mots-clé
Humans, Radiotherapy Dosage, Animals, Neoplasms/radiotherapy, FLASH radiotherapy, Recording, Reporting, Terminology, Ultra-high dose rate radiotherapy
Pubmed
Web of science
Création de la notice
13/09/2024 15:06
Dernière modification de la notice
11/10/2024 19:14
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