Molecular RHD screening of RhD negative donors can replace standard serological testing for RhD negative donors.
Détails
ID Serval
serval:BIB_DF8EE2BB43EE
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Molecular RHD screening of RhD negative donors can replace standard serological testing for RhD negative donors.
Périodique
Transfusion and Apheresis Science
ISSN
1473-0502 (Print)
ISSN-L
1473-0502
Statut éditorial
Publié
Date de publication
2014
Peer-reviewed
Oui
Volume
50
Numéro
2
Pages
163-168
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't Publication Status: ppublish, pdf :Review
Résumé
This work aims to assess the value of a generalized molecular RHD screening strategy which could replace routine serological screening of weak D by indirect antiglobulin test. Three independent studies were performed at the two Blood Transfusion Services Berne and Zurich. Donors investigated were 652 RhD negative, but RhC and/or RhE positive, 17,391 mainly Rhccee, and 8200 with normal RhCcEe phenotype distribution. In study I single samples, in studies II and III minipools of 24 and 20 donor samples were tested, respectively. Among 26,243 phenotypically RhD negative blood donors, 65 carriers of RHD alleles were identified. Thirty-one of them were redefined as RhD positive.
Pubmed
Web of science
Création de la notice
09/11/2014 18:24
Dernière modification de la notice
20/08/2019 17:03
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