Vim stereotactic radiosurgical thalamotomy for drug-resistant idiopathic Holmes tremor: a case report.
Détails
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Accès restreint UNIL
Etat: Public
Version: Final published version
Licence: Non spécifiée
ID Serval
serval:BIB_DD9D46FC332C
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Institution
Titre
Vim stereotactic radiosurgical thalamotomy for drug-resistant idiopathic Holmes tremor: a case report.
Périodique
Acta neurochirurgica
ISSN
0942-0940 (Electronic)
ISSN-L
0001-6268
Statut éditorial
Publié
Date de publication
07/2021
Peer-reviewed
Oui
Volume
163
Numéro
7
Pages
1867-1871
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Résumé
We share our experience with stereotactic gamma knife thalamotomy (GKT) for medically refractory Holmes tremor (HT). A 22-year-old patient underwent gamma knife thalamotomy at ventrointermediate nucleus for disabling HT of the right upper limb. A single 4-mm isocenter was used to target the ventral intermediate nucleus with 130 Gy radiation. At 4 months follow up, we observed 84% improvement in his Fahn-Tolosa-Marin (FTM) rating scale with significant improvement in the right upper limb dystonic tremor. There was only subtle improvement in the ataxic component of the right lower limb. At 1 year after stereotactic GKT, there was sustained neurological improvement with no side effect, We present the stereotactic GKT as a treatment modality for drug-resistant HT. Moreover, it may be considered an alternate treatment modality especially in patients reluctant or contraindicated for any invasive surgical technique. CLINICAL TRIAL REGISTRATION NUMBER: Not required.
Mots-clé
Dystonia, Midbrain tremor, Rubral tremor, Thalamotomy
Pubmed
Web of science
Financement(s)
Université de Lausanne / CRND-31188
Création de la notice
24/07/2020 14:23
Dernière modification de la notice
14/08/2022 6:39