Vim stereotactic radiosurgical thalamotomy for drug-resistant idiopathic Holmes tremor: a case report.

Details

Serval ID
serval:BIB_DD9D46FC332C
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Vim stereotactic radiosurgical thalamotomy for drug-resistant idiopathic Holmes tremor: a case report.
Journal
Acta neurochirurgica
Author(s)
Tripathi M., Mehta S., Singla R., Ahuja C.K., Tandalya N., Tuleasca C., Batish A., Mohindra S., Agrahari A., Kaur R.
ISSN
0942-0940 (Electronic)
ISSN-L
0001-6268
Publication state
In Press
Peer-reviewed
Oui
Language
english
Notes
Publication types: Journal Article
Publication Status: aheadofprint
Abstract
We share our experience with stereotactic gamma knife thalamotomy (GKT) for medically refractory Holmes tremor (HT). A 22-year-old patient underwent gamma knife thalamotomy at ventrointermediate nucleus for disabling HT of the right upper limb. A single 4-mm isocenter was used to target the ventral intermediate nucleus with 130 Gy radiation. At 4 months follow up, we observed 84% improvement in his Fahn-Tolosa-Marin (FTM) rating scale with significant improvement in the right upper limb dystonic tremor. There was only subtle improvement in the ataxic component of the right lower limb. At 1 year after stereotactic GKT, there was sustained neurological improvement with no side effect, We present the stereotactic GKT as a treatment modality for drug-resistant HT. Moreover, it may be considered an alternate treatment modality especially in patients reluctant or contraindicated for any invasive surgical technique. CLINICAL TRIAL REGISTRATION NUMBER: Not required.
Keywords
Dystonia, Midbrain tremor, Rubral tremor, Thalamotomy
Pubmed
Funding(s)
University of Lausanne / CRND-31188
Create date
24/07/2020 14:23
Last modification date
02/09/2020 6:22
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