Ten years of R&D and full automation in molecular diagnosis.
Détails
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Accès restreint UNIL
Etat: Public
Version: Final published version
ID Serval
serval:BIB_DD3A1054F7C7
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Ten years of R&D and full automation in molecular diagnosis.
Périodique
Future Microbiology
ISSN
1746-0921 (Electronic)
ISSN-L
1746-0913
Statut éditorial
Publié
Date de publication
2016
Peer-reviewed
Oui
Volume
11
Pages
403-425
Langue
anglais
Résumé
A 10-year experience of our automated molecular diagnostic platform that carries out 91 different real-time PCR is described. Progresses and future perspectives in molecular diagnostic microbiology are reviewed: why automation is important; how our platform was implemented; how homemade PCRs were developed; the advantages/disadvantages of homemade PCRs, including the critical aspects of troubleshooting and the need to further reduce the turnaround time for specific samples, at least for defined clinical settings such as emergencies. The future of molecular diagnosis depends on automation, and in a novel perspective, it is time now to fully acknowledge the true contribution of molecular diagnostic and to reconsider the indication for PCR, by also using these tests as first-line assays.
Pubmed
Web of science
Open Access
Oui
Création de la notice
09/04/2016 16:05
Dernière modification de la notice
20/08/2019 17:02