Squamous-cell carcinoma arising in a non-irradiated child with recurrent respiratory papillomatosis.

Détails

ID Serval
serval:BIB_DC973C5BE40C
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Institution
Titre
Squamous-cell carcinoma arising in a non-irradiated child with recurrent respiratory papillomatosis.
Périodique
European journal of pediatrics
Auteur(s)
Simma B., Burger R., Uehlinger J., Ghelfi D., Hof E., Dangel P., Briner J., Fanconi S.
ISSN
0340-6199
Statut éditorial
Publié
Date de publication
1993
Peer-reviewed
Oui
Volume
152
Numéro
9
Pages
776-8
Langue
anglais
Notes
Publication types: Case Reports ; Journal Article ; Review - Publication Status: ppublish
Résumé
We describe a patient with recurrent respiratory papillomatosis (RRP) associated with human papilloma virus (HPV), who developed a fatal squamous cell carcinoma of the lung. At the age of 1 year he presented with hoarseness, dyspnoea and inspiratory stridor but the diagnosis of RRP was made only 1 year later. At the age of 4 years he was tracheostomized because of upper airway obstruction. In spite of multiple surgical excisions and topic treatment with 5-fluorouracil the papillomata extended to the lung parenchyma. At the age of 16 years he developed a squamous-cell carcinoma of the lung and died 4 months later. Transformation to pulmonary carcinoma is a rare complication in non-irradiated patients with lung papillomatosis. We found only 11 similar cases in the literature.
Mots-clé
Adolescent, Carcinoma, Squamous Cell, Cell Transformation, Neoplastic, Humans, Lung Neoplasms, Male, Neoplasm Recurrence, Local, Papilloma, Papillomaviridae, Papillomavirus Infections, Respiratory Tract Neoplasms, Tumor Virus Infections
Pubmed
Web of science
Création de la notice
25/01/2008 10:06
Dernière modification de la notice
20/08/2019 16:01
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