Control of plant phosphate homeostasis by inositol pyrophosphates and the SPX domain.
Détails
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Etat: Public
Version: Author's accepted manuscript
Etat: Public
Version: Author's accepted manuscript
ID Serval
serval:BIB_D95F2287121D
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Control of plant phosphate homeostasis by inositol pyrophosphates and the SPX domain.
Périodique
Current opinion in biotechnology
ISSN
1879-0429 (Electronic)
ISSN-L
0958-1669
Statut éditorial
Publié
Date de publication
02/2018
Peer-reviewed
Oui
Volume
49
Pages
156-162
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Review
Publication Status: ppublish
Publication Status: ppublish
Résumé
Proteins containing a SPX domain are involved in phosphate (Pi) homeostasis, including Pi transport and adaptation to Pi deficiency. The SPX domain harbors a basic surface binding Pi at low affinity and inositol pyrophosphates (PP-InsPs) at high affinity. Genetic and biochemical studies revealed that PP-InsPs serve as ligands for the SPX domain. Residues in the PHO1 SPX domain involved in PP-InsPs binding are critical for its Pi export activity, and the interaction between SPX proteins and the PHR1 transcription factor, which results in PHR1 inactivation, is promoted by PP-InsPs. Changes in PP-InsPs levels in response to Pi deficiency may thus contribute to the adaptation of plants to stress via the modulation of the activity of SPX-containing proteins and their interactors. Modulating PP-InsP levels or the affinity/specificity of the SPX domain for PP-InsP could potentially be used to engineer crops to maintain high yield under reduced Pi fertilizer input.
Mots-clé
Biological Transport, Homeostasis, Inositol Phosphates/metabolism, Phosphates/metabolism, Plants/chemistry, Plants/metabolism, Transcription Factors/metabolism
Pubmed
Web of science
Création de la notice
13/03/2018 15:38
Dernière modification de la notice
21/11/2022 8:26