Idiopathic recurrent neuroretinitis: effects of long-term immunosuppression.

Détails

ID Serval
serval:BIB_D58B29C0669F
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Idiopathic recurrent neuroretinitis: effects of long-term immunosuppression.
Périodique
Archives of ophthalmology
Auteur(s)
Purvin V., Ranson N., Kawasaki A.
ISSN
0003-9950
Statut éditorial
Publié
Date de publication
2003
Peer-reviewed
Oui
Volume
121
Numéro
1
Pages
65-7
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Résumé
OBJECTIVE: To determine the efficacy of long-term immunosuppressive therapy in patients with recurrent idiopathic neuroretinitis. METHODS: A retrospective review of 30 patients with recurrent idiopathic neuroretinitis identified 7 who received ongoing immunosuppression with prednisone and/or azathioprine for whom adequate follow-up information was available. We calculated the number of attacks per unit of time for each patient before and after treatment to derive mean attack rates for the group. RESULTS: For the entire group, we found a rate of 0.58 attacks per year prior to the initiation of immunosuppressive treatment, which decreased to 0.16 attacks per year following immunosuppression. This represents a reduction in the attack rate of 0.41, or a 72% decrease in attack frequency. CONCLUSIONS: Our study suggests a possible role for long-term immunosuppressive treatment in patients with recurrent idiopathic neuroretinitis. A longer follow-up interval, more standardized treatment regimens, and additional outcome measures might reveal a greater benefit of treatment.
Mots-clé
Adult, Azathioprine/therapeutic use, Drug Therapy, Combination, Female, Follow-Up Studies, Humans, Immunosuppression, Immunosuppressive Agents/therapeutic use, Male, Prednisone/therapeutic use, Recurrence, Retinitis/diagnosis, Retinitis/drug therapy, Retrospective Studies
Pubmed
Web of science
Création de la notice
23/11/2009 10:45
Dernière modification de la notice
20/08/2019 16:55
Données d'usage