Paraproteins and complement depletion: pathogenesis and clinical syndromes
Détails
ID Serval
serval:BIB_D4419B49A3F0
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Paraproteins and complement depletion: pathogenesis and clinical syndromes
Périodique
Seminars in Hematology
ISSN
0037-1963
Statut éditorial
Publié
Date de publication
01/1997
Peer-reviewed
Oui
Volume
34
Numéro
1 Suppl 1
Pages
40-8
Notes
Journal Article
Review --- Old month value: Jan
Review --- Old month value: Jan
Résumé
Various clinical syndromes that associate paraproteinemia and complement depletion have been described in the last three decades. Among these, cryoglobulinemias, acquired Clq deficiency, and acquired deficiencies of the classical pathway of complement can be associated with B-cell lymphoproliferative disorders. Some specific symptoms should alert the clinician to suspect an underlying malignancy. In this report, we review the pathogenesis, symptomatology and therapeutic options of these clinical conditions.
Mots-clé
Agammaglobulinemia/physiopathology
Complement C1q/deficiency
Complement Pathway, Alternative/physiology
Complement System Proteins/*metabolism
Cryoglobulinemia/etiology
Glomerulonephritis/etiology
Humans
Paraproteinemias/*etiology/metabolism
Syndrome
Pubmed
Web of science
Création de la notice
29/01/2008 14:52
Dernière modification de la notice
20/08/2019 16:54