Epidemiology of hypospadias in Europe: a registry-based study.

Détails

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Etat: Public
Version: Final published version
Licence: Non spécifiée
ID Serval
serval:BIB_D2139E13E20F
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Epidemiology of hypospadias in Europe: a registry-based study.
Périodique
World Journal of Urology
Auteur(s)
Bergman J.E., Loane M., Vrijheid M., Pierini A., Nijman R.J., Addor M.C., Barisic I., Béres J., Braz P., Budd J., Delaney V., Gatt M., Khoshnood B., Klungsøyr K., Martos C., Mullaney C., Nelen V., Neville A.J., O'Mahony M., Queisser-Luft A., Randrianaivo H., Rissmann A., Rounding C., Tucker D., Wellesley D., Zymak-Zakutnia N., Bakker M.K., de Walle H.E.
ISSN
1433-8726 (Electronic)
ISSN-L
0724-4983
Statut éditorial
Publié
Date de publication
2015
Peer-reviewed
Oui
Volume
33
Numéro
12
Pages
2159-2167
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Résumé
BACKGROUND: Hypospadias is a common congenital malformation. The prevalence of hypospadias has a large geographical variation, and recent studies have reported both increasing and decreasing temporal trends. It is unclear whether hypospadias prevalence is associated with maternal age.
AIM: To analyze the prevalence and trends of total hypospadias, isolated hypospadias, hypospadias with multiple congenital anomalies, hypospadias with a known cause, and hypospadias severity subtypes in Europe over a 10-year period and to investigate whether maternal age is associated with hypospadias.
METHODS: We included all children with hypospadias born from 2001 to 2010 who were registered in 23 EUROCAT registries. Information on the total number of births and maternal age distribution for the registry population was also provided. We analyzed the total prevalence of hypospadias and relative risks by maternal age.
RESULTS: From 2001 to 2010, 10,929 hypospadias cases were registered in 5,871,855 births, yielding a total prevalence of 18.61 per 10,000 births. Prevalence varied considerably between different registries, probably due to differences in ascertainment of hypospadias cases. No significant temporal trends were observed with the exceptions of an increasing trend for anterior and posterior hypospadias and a decreasing trend for unspecified hypospadias. After adjusting for registry effects, maternal age was not significantly associated with hypospadias.
CONCLUSIONS: Total hypospadias prevalence was stable in 23 EUROCAT registries from 2001 to 2010 and was not significantly influenced by maternal age.
Mots-clé
Europe/epidemiology, Female, Humans, Hypospadias/complications, Hypospadias/epidemiology, Infant, Newborn, Male, Maternal Age, Prevalence, Registries, Risk Factors
Pubmed
Web of science
Open Access
Oui
Création de la notice
26/01/2016 9:11
Dernière modification de la notice
20/08/2019 15:52
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