In vivo 13C NMR spectroscopy and metabolic modeling in the brain: a practical perspective.

Henry, P.G.; Adriany, G.; Deelchand, D.; Gruetter, R.; Marjanska, M.; Oz, G.; Seaquist, E.R.; Shestov, A.; Uğurbil, K.

doi:10.1016/j.mri.2006.01.003

In vivo 13C NMR spectroscopy and metabolic modeling in the brain: a practical perspective.

Détails

Demande d'une copie

ID Serval

serval:BIB_D04D3CFB5137

Type

Article: article d'un périodique ou d'un magazine.

Sous-type

Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.

Collection

Publications

Institution

UNIL/CHUV

Titre

In vivo 13C NMR spectroscopy and metabolic modeling in the brain: a practical perspective.

Périodique

Magnetic Resonance Imaging

Auteur⸱e⸱s

Henry P.G., Adriany G., Deelchand D., Gruetter R., Marjanska M., Oz G., Seaquist E.R., Shestov A., Uğurbil K.

ISSN

0730-725X[print], 0730-725X[linking]

Statut éditorial

Publié

Date de publication

2006

Volume

Numéro

Pages

527-539

Langue

anglais

Notes

Publication types: Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
Publication Status: ppublish

Résumé

In vivo 13C NMR spectroscopy has the unique capability to measure metabolic fluxes noninvasively in the brain. Quantitative measurements of metabolic fluxes require analysis of the 13C labeling time courses obtained experimentally with a metabolic model. The present work reviews the ingredients necessary for a dynamic metabolic modeling study, with particular emphasis on practical issues.

Mots-clé

Animals, Brain/metabolism, Carbon Radioisotopes, Magnetic Resonance Spectroscopy, Models, Biological, Rats

OAI-PMH

oai:serval.unil.ch:BIB_D04D3CFB5137

DOI

10.1016/j.mri.2006.01.003

Pubmed

16677959

Web of science

000237711000023

Création de la notice

04/08/2010 15:28