Recurrent febrile panniculitis and hepatitis in two patients with acquired complement deficiency and paraproteinemia
Détails
ID Serval
serval:BIB_CDFCAF324EB7
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Institution
Titre
Recurrent febrile panniculitis and hepatitis in two patients with acquired complement deficiency and paraproteinemia
Périodique
American Journal of Medicine
ISSN
0002-9343
Statut éditorial
Publié
Date de publication
11/1987
Peer-reviewed
Oui
Volume
83
Numéro
5
Pages
959-62
Notes
Case Reports
Journal Article
Research Support, Non-U.S. Gov't --- Old month value: Nov
Journal Article
Research Support, Non-U.S. Gov't --- Old month value: Nov
Résumé
Repeated episodes of febrile panniculitis and hepatitis were the main clinical features in two patients with an IgG1 kappa paraproteinemia and severe depletion of the early components of the classical pathway of complement (acquired C1 inhibitor deficiency). They did not have episodes of cutaneous angioedema or evidence of immune complex disease. In the more severely affected patient, the episodes responded to steroids. These features have not been described with acquired C1 inhibitor deficiency and may be related to complement activation.
Mots-clé
Complement Activation
Complement C1 Inactivator Proteins/*deficiency
Hepatitis/*immunology
Humans
Immunoglobulin kappa-Chains/*immunology
Male
Middle Aged
Panniculitis, Nodular Nonsuppurative/*immunology
Paraproteinemias/*immunology
Recurrence
Pubmed
Web of science
Création de la notice
29/01/2008 14:52
Dernière modification de la notice
20/08/2019 16:48