La lymphocytose B polyclonale persistante: un syndrome lymphoproliferatif benin. [Persistent B-cell polyclonal lymphocytosis: a benign lymphoproliferative syndrome]

Détails

ID Serval
serval:BIB_CCD0A7E3644B
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Institution
Titre
La lymphocytose B polyclonale persistante: un syndrome lymphoproliferatif benin. [Persistent B-cell polyclonal lymphocytosis: a benign lymphoproliferative syndrome]
Périodique
Schweizerische Medizinische Wochenschrift
Auteur(s)
Tissot  J. D., Schmidt  P. M., von Fliedner  V., Knecht  H.
ISSN
0036-7672 (Print)
Statut éditorial
Publié
Date de publication
10/1991
Volume
121
Numéro
43
Pages
1582-4
Notes
Case Reports
English Abstract
Journal Article --- Old month value: Oct 26
Résumé
A further case of persistent polyclonal B-cell lymphocytosis is reported. This recently identified distinct clinicopathologic entity is frequently associated with the presence of the HLA-DR7 antigen. It follows a benign course and has so far been reported only in women smokers. The disorder is characterized by mild chronic peripheral lymphocytosis, the presence of characteristic binucleate lymphocytes on peripheral blood smears, and a polyclonal increase in serum IgM. In some cases, lymphadenopathies and/or splenomegaly are observed. Surface marker studies of peripheral lymphocytes demonstrate the polyclonal B-cell nature of this entity.
Mots-clé
Adult *B-Lymphocytes/immunology/pathology Female HLA-DR7 Antigen/isolation & purification Humans Immunoglobulin M/isolation & purification Lymphocytosis/*blood/immunology Lymphoproliferative Disorders/*blood Smoking/blood
Pubmed
Web of science
Création de la notice
25/01/2008 16:34
Dernière modification de la notice
20/08/2019 16:47
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