La lymphocytose B polyclonale persistante: un syndrome lymphoproliferatif benin. [Persistent B-cell polyclonal lymphocytosis: a benign lymphoproliferative syndrome]
Details
Serval ID
serval:BIB_CCD0A7E3644B
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
La lymphocytose B polyclonale persistante: un syndrome lymphoproliferatif benin. [Persistent B-cell polyclonal lymphocytosis: a benign lymphoproliferative syndrome]
Journal
Schweizerische Medizinische Wochenschrift
ISSN
0036-7672 (Print)
Publication state
Published
Issued date
10/1991
Volume
121
Number
43
Pages
1582-4
Notes
Case Reports
English Abstract
Journal Article --- Old month value: Oct 26
English Abstract
Journal Article --- Old month value: Oct 26
Abstract
A further case of persistent polyclonal B-cell lymphocytosis is reported. This recently identified distinct clinicopathologic entity is frequently associated with the presence of the HLA-DR7 antigen. It follows a benign course and has so far been reported only in women smokers. The disorder is characterized by mild chronic peripheral lymphocytosis, the presence of characteristic binucleate lymphocytes on peripheral blood smears, and a polyclonal increase in serum IgM. In some cases, lymphadenopathies and/or splenomegaly are observed. Surface marker studies of peripheral lymphocytes demonstrate the polyclonal B-cell nature of this entity.
Keywords
Adult
*B-Lymphocytes/immunology/pathology
Female
HLA-DR7 Antigen/isolation & purification
Humans
Immunoglobulin M/isolation & purification
Lymphocytosis/*blood/immunology
Lymphoproliferative Disorders/*blood
Smoking/blood
Pubmed
Web of science
Create date
25/01/2008 16:34
Last modification date
20/08/2019 16:47