The Drosophila zinc finger transcription factor CF2 is a myogenic marker downstream of MEF2 during muscle development.

Détails

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ID Serval
serval:BIB_CAE8F4F16E11
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Production externe
Titre
The Drosophila zinc finger transcription factor CF2 is a myogenic marker downstream of MEF2 during muscle development.
Périodique
Mechanisms of development
Auteur⸱e⸱s
Bagni C., Bray S., Gogos J.A., Kafatos F.C., Hsu T.
ISSN
0925-4773 (Print)
ISSN-L
0925-4773
Statut éditorial
Publié
Date de publication
09/2002
Volume
117
Numéro
1-2
Pages
265-268
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, U.S. Gov't, P.H.S.
Publication Status: ppublish
Résumé
The Drosophila C(2)-H(2)-type zinc-finger transcription factor CF2 has been shown to regulate follicular cell fate determination during oogenesis. Here we show that CF2 is also expressed in the developing muscles of the embryo where it first appears at stage 12 at the time of skeletal myoblast fusion. Later it is expressed in all muscle lineages including skeletal, visceral and cardiac. Epistatic analysis showed that CF2 expression is dependent on the myogenic factor MEF2.

Mots-clé
Animals, DNA-Binding Proteins/genetics, DNA-Binding Proteins/metabolism, Drosophila/embryology, Drosophila/genetics, Drosophila/metabolism, Drosophila Proteins/genetics, Drosophila Proteins/metabolism, Gene Expression Regulation, Developmental, Genes, Insect, Immunohistochemistry, MEF2 Transcription Factors, Muscles/embryology, Muscles/metabolism, Myogenic Regulatory Factors, Transcription Factors/genetics, Transcription Factors/metabolism, Zinc Fingers/genetics
Pubmed
12204268
Création de la notice
06/03/2017 18:23
Dernière modification de la notice
20/08/2019 16:45
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