The Drosophila zinc finger transcription factor CF2 is a myogenic marker downstream of MEF2 during muscle development.

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Serval ID
serval:BIB_CAE8F4F16E11
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Production externe
Title
The Drosophila zinc finger transcription factor CF2 is a myogenic marker downstream of MEF2 during muscle development.
Journal
Mechanisms of development
Author(s)
Bagni C., Bray S., Gogos J.A., Kafatos F.C., Hsu T.
ISSN
0925-4773 (Print)
ISSN-L
0925-4773
Publication state
Published
Issued date
09/2002
Volume
117
Number
1-2
Pages
265-268
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, U.S. Gov't, P.H.S.
Publication Status: ppublish
Abstract
The Drosophila C(2)-H(2)-type zinc-finger transcription factor CF2 has been shown to regulate follicular cell fate determination during oogenesis. Here we show that CF2 is also expressed in the developing muscles of the embryo where it first appears at stage 12 at the time of skeletal myoblast fusion. Later it is expressed in all muscle lineages including skeletal, visceral and cardiac. Epistatic analysis showed that CF2 expression is dependent on the myogenic factor MEF2.

Keywords
Animals, DNA-Binding Proteins/genetics, DNA-Binding Proteins/metabolism, Drosophila/embryology, Drosophila/genetics, Drosophila/metabolism, Drosophila Proteins/genetics, Drosophila Proteins/metabolism, Gene Expression Regulation, Developmental, Genes, Insect, Immunohistochemistry, MEF2 Transcription Factors, Muscles/embryology, Muscles/metabolism, Myogenic Regulatory Factors, Transcription Factors/genetics, Transcription Factors/metabolism, Zinc Fingers/genetics
Pubmed
12204268
Create date
06/03/2017 17:23
Last modification date
20/08/2019 15:45
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