Simultaneous topography-guided photorefractive keratectomy followed by corneal collagen cross-linking for keratoconus.

Détails

ID Serval
serval:BIB_C692731B64A3
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Simultaneous topography-guided photorefractive keratectomy followed by corneal collagen cross-linking for keratoconus.
Périodique
American journal of ophthalmology
Auteur(s)
Kymionis G.D., Portaliou D.M., Kounis G.A., Limnopoulou A.N., Kontadakis G.A., Grentzelos M.A.
ISSN
1879-1891 (Electronic)
ISSN-L
0002-9394
Statut éditorial
Publié
Date de publication
11/2011
Peer-reviewed
Oui
Volume
152
Numéro
5
Pages
748-755
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
To present the long-term results after simultaneous photorefractive keratectomy followed by corneal collagen cross-linking for keratoconus.
Prospective, interventional, consecutive case series.
In this study, 26 patients (31 eyes) with progressive keratoconus were included. All patients underwent customized topography-guided photorefractive keratectomy immediately followed by corneal collagen cross-linking with the use of riboflavin and ultraviolet A irradiation. Epithelium was removed by transepithelial phototherapeutic keratectomy in all cases.
Mean follow-up was 19.53 ± 3.97 months (range, 12 to 25 months). Mean preoperative spherical equivalent was -2.3 ± 2.8 diopters (D), whereas at the last follow-up examination, it was significantly (P < .001) reduced to -1.08 ± 2.41 D. Logarithm of the minimal angle of resolution uncorrected and best-corrected visual acuity were reduced significantly by 0.46 and 0.084 (P < .001), respectively, at the last follow-up examination. Finally, mean steep and flat keratometry readings were reduced by 2.35 (P < .001) and 1.18 (P = .013) at the last follow-up examination.
Simultaneous photorefractive keratectomy followed by corneal collagen cross-linking seems to be a promising treatment alternative in our series of keratoconic patients.
Mots-clé
Adult, Collagen/metabolism, Combined Modality Therapy, Corneal Stroma/metabolism, Corneal Topography, Cross-Linking Reagents, Female, Follow-Up Studies, Humans, Keratoconus/drug therapy, Keratoconus/physiopathology, Keratoconus/surgery, Keratoconus/therapy, Lasers, Excimer/therapeutic use, Male, Middle Aged, Photochemotherapy, Photorefractive Keratectomy, Photosensitizing Agents/therapeutic use, Prospective Studies, Refraction, Ocular/physiology, Riboflavin/therapeutic use, Treatment Outcome, Ultraviolet Rays, Visual Acuity/physiology, Young Adult
Pubmed
Web of science
Création de la notice
01/10/2019 14:16
Dernière modification de la notice
06/10/2019 5:26
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