Snapshot summary of diagnosis and management of hepatocellular adenoma subtypes.

Détails

ID Serval
serval:BIB_C6669E976839
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Snapshot summary of diagnosis and management of hepatocellular adenoma subtypes.
Périodique
Clinics and research in hepatology and gastroenterology
Auteur⸱e⸱s
Bioulac-Sage P., Sempoux C., Frulio N., Le Bail B., Blanc J.F., Castain C., Laurent C., Trillaud H., Chiche L., Balabaud C.
ISSN
2210-741X (Electronic)
ISSN-L
2210-7401
Statut éditorial
Publié
Date de publication
02/2019
Peer-reviewed
Oui
Volume
43
Numéro
1
Pages
12-19
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
PDF: Mini review
Résumé
Hepatocellular adenomas (HCA) are rare benign hepatocellular tumors occurring mainly in women taking oral contraceptives with 2 major complications: severe bleeding and malignant transformation that can be avoided if nodules exceeding 5 cm are resected. This simple attitude has been challenged in the recent years with HCA in men, in young adolescent, in aged persons, and complications in hepatocellular adenomas below 5 cm. The discovery of specific mutations leading to specific phenotypes has modified the clinical spectrum of the disease. The phenotypic immune classification of HCA based on the molecular classification is being widely used in liver referral centers. The aim of this snapshot is to briefly present for each subtype the clinical, pathological, immuno-pathological criteria as well as the risk of complications and guidelines for treatment and management.
Mots-clé
Hepatocellular adenoma, Immunohistochemical classification, Overview
Pubmed
Web of science
Création de la notice
19/09/2018 10:18
Dernière modification de la notice
20/08/2019 16:41
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