Snapshot summary of diagnosis and management of hepatocellular adenoma subtypes.

Details

Serval ID
serval:BIB_C6669E976839
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Snapshot summary of diagnosis and management of hepatocellular adenoma subtypes.
Journal
Clinics and research in hepatology and gastroenterology
Author(s)
Bioulac-Sage P., Sempoux C., Frulio N., Le Bail B., Blanc J.F., Castain C., Laurent C., Trillaud H., Chiche L., Balabaud C.
ISSN
2210-741X (Electronic)
ISSN-L
2210-7401
Publication state
Published
Issued date
02/2019
Peer-reviewed
Oui
Volume
43
Number
1
Pages
12-19
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
PDF: Mini review
Abstract
Hepatocellular adenomas (HCA) are rare benign hepatocellular tumors occurring mainly in women taking oral contraceptives with 2 major complications: severe bleeding and malignant transformation that can be avoided if nodules exceeding 5 cm are resected. This simple attitude has been challenged in the recent years with HCA in men, in young adolescent, in aged persons, and complications in hepatocellular adenomas below 5 cm. The discovery of specific mutations leading to specific phenotypes has modified the clinical spectrum of the disease. The phenotypic immune classification of HCA based on the molecular classification is being widely used in liver referral centers. The aim of this snapshot is to briefly present for each subtype the clinical, pathological, immuno-pathological criteria as well as the risk of complications and guidelines for treatment and management.
Keywords
Hepatocellular adenoma, Immunohistochemical classification, Overview
Pubmed
Web of science
Create date
19/09/2018 10:18
Last modification date
20/08/2019 16:41
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