Prophylaxis failure is associated with a specific Pneumocystis carinii genotype.

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Etat: Public
Version: Final published version
Licence: Non spécifiée
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ID Serval
serval:BIB_C663940A6537
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Prophylaxis failure is associated with a specific Pneumocystis carinii genotype.
Périodique
Clinical Infectious Diseases
Auteur⸱e⸱s
Hauser P.M., Sudre P., Nahimana A., Francioli P.
Collaborateur⸱rice⸱s
Study Group
ISSN
1058-4838 (Print)
ISSN-L
1058-4838
Statut éditorial
Publié
Date de publication
10/2001
Peer-reviewed
Oui
Volume
33
Numéro
7
Pages
1080-1082
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Résumé
To investigate the possible association between Pneumocystis carinii types and various clinical and demographic parameters, we used molecular typing to analyze 93 bronchoalveolar lavage specimens from patients with P. carinii pneumonia (PCP). Multivariate regression analysis revealed an association between being infected with a specific P. carinii genotype and receiving anti-PCP prophylaxis (odds ratio, 4.4; 95% confidence interval, 1.0-18.6; P=.05), although no association with a specific drug was detected.
Mots-clé
Adult, Aged, Antifungal Agents/therapeutic use, Bronchoalveolar Lavage Fluid/microbiology, Female, Genotype, Humans, Male, Middle Aged, Mycological Typing Techniques, Pneumocystis/classification, Pneumocystis/genetics, Pneumonia, Pneumocystis/microbiology, Pneumonia, Pneumocystis/prevention & control, Polymerase Chain Reaction, Polymorphism, Single-Stranded Conformational, Treatment Failure
Pubmed
Web of science
Open Access
Oui
Création de la notice
25/01/2008 17:07
Dernière modification de la notice
14/02/2022 7:57
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