Delayed B-cell maturation and attenuated vaccine responses in infants exposed to B-cell depleting therapies in utero.
Détails
Etat: Public
Version: Final published version
Licence: CC BY 4.0
ID Serval
serval:BIB_C2B7DF829581
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Delayed B-cell maturation and attenuated vaccine responses in infants exposed to B-cell depleting therapies in utero.
Périodique
The journal of allergy and clinical immunology. In practice
ISSN
2213-2201 (Electronic)
Statut éditorial
Publié
Date de publication
11/2024
Peer-reviewed
Oui
Volume
12
Numéro
11
Pages
3155-3158.e1
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Résumé
In utero exposure to anti-CD20 monoclonal antibodies can result in transient B-cell depletion, delayed B-cell maturation, decreased immunoglobulin production and inadequate vaccine responses in the infant. These children require immunological follow up and personalized vaccine schedules.
Mots-clé
Krec, in utero exposure, kappa-deleting recombination excision circles, neonatal screening, obinutuzumab, rituximab, vaccine responses, KREC
Pubmed
Open Access
Oui
Création de la notice
19/08/2024 8:20
Dernière modification de la notice
20/11/2024 7:27
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