Incidence of childhood acute lymphoblastic leukemia (ALL) and population-based treatment results in Switzerland: experiences with 507 study and 149 nonstudy patients

Détails

ID Serval
serval:BIB_BD7EAFD60540
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Incidence of childhood acute lymphoblastic leukemia (ALL) and population-based treatment results in Switzerland: experiences with 507 study and 149 nonstudy patients
Périodique
Medical and Pediatric Oncology
Auteur⸱e⸱s
Stupnicki  A., von der Weid  N., Imbach  P., Arnet  B., Berchtold  W., Delaleu  B., Hirt  A., Pluess  H. J., Beck  D., Wyss  M., Luethy  A.R., Feldges  A., Signer  E., Morin  A.M., Caflisch  U., Leibundgut  K., Frey  E., Kuechler  H., Baumgartner  C., Bleher  E.A., Angst  R., Blauenstein  U., Nobile  L., Vischer  D., Wagner  H.P.
ISSN
0098-1532 (Print)
Statut éditorial
Publié
Date de publication
08/1995
Volume
25
Numéro
2
Pages
79-83
Notes
Journal Article --- Old month value: Aug
Résumé
Of 656 patients with ALL (all types) diagnosed in Switzerland during 4 consecutive 4-year periods (1976-1979, 1980-1983, 1984-1987, 1988-1991), 507 were officially registered on protocols ("study" patients) while 149 were not ("nonstudy" patients). The mean incidence of 3.8/100,000 children < 15 years/year is higher than reported for other Western countries. Evidence is presented suggesting that the 656 patients represent only approximately 90% of all children with ALL residing in Switzerland, indicating that the true incidence of ALL might even be higher. The fraction of "nonstudy" patients fell from 40% (1976-1979) to 15% (1984-1987). The rate of survival at 4 years of all patients with ALL ("study" and "nonstudy") increased by 17% during the three consecutive periods 1976-1979, 1980-1983, and 1984-1987. As expected, a higher increase (20%) was observed in "study" patients and a statistically nonsignificant lower one (10%) in "nonstudy" patients.
Mots-clé
Adolescent Child Child, Preschool Humans Incidence Infant Leukemia, Lymphocytic, Acute, L1/*epidemiology Survival Analysis Switzerland/epidemiology
Pubmed
Web of science
Création de la notice
25/01/2008 11:35
Dernière modification de la notice
20/08/2019 16:31
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