Incidence of childhood acute lymphoblastic leukemia (ALL) and population-based treatment results in Switzerland: experiences with 507 study and 149 nonstudy patients
Details
Serval ID
serval:BIB_BD7EAFD60540
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Incidence of childhood acute lymphoblastic leukemia (ALL) and population-based treatment results in Switzerland: experiences with 507 study and 149 nonstudy patients
Journal
Medical and Pediatric Oncology
ISSN
0098-1532 (Print)
Publication state
Published
Issued date
08/1995
Volume
25
Number
2
Pages
79-83
Notes
Journal Article --- Old month value: Aug
Abstract
Of 656 patients with ALL (all types) diagnosed in Switzerland during 4 consecutive 4-year periods (1976-1979, 1980-1983, 1984-1987, 1988-1991), 507 were officially registered on protocols ("study" patients) while 149 were not ("nonstudy" patients). The mean incidence of 3.8/100,000 children < 15 years/year is higher than reported for other Western countries. Evidence is presented suggesting that the 656 patients represent only approximately 90% of all children with ALL residing in Switzerland, indicating that the true incidence of ALL might even be higher. The fraction of "nonstudy" patients fell from 40% (1976-1979) to 15% (1984-1987). The rate of survival at 4 years of all patients with ALL ("study" and "nonstudy") increased by 17% during the three consecutive periods 1976-1979, 1980-1983, and 1984-1987. As expected, a higher increase (20%) was observed in "study" patients and a statistically nonsignificant lower one (10%) in "nonstudy" patients.
Keywords
Adolescent Child Child, Preschool Humans Incidence Infant Leukemia, Lymphocytic, Acute, L1/*epidemiology Survival Analysis Switzerland/epidemiology
Pubmed
Web of science
Create date
25/01/2008 10:35
Last modification date
20/08/2019 15:31