Trabecular bone score (TBS) as a new complementary approach for osteoporosis evaluation in clinical practice.
Détails
Etat: Public
Version: de l'auteur⸱e
ID Serval
serval:BIB_BCDB78CE284B
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Trabecular bone score (TBS) as a new complementary approach for osteoporosis evaluation in clinical practice.
Périodique
Bone
ISSN
1873-2763 (Electronic)
ISSN-L
1873-2763
Statut éditorial
Publié
Date de publication
2015
Peer-reviewed
Oui
Volume
78
Pages
216-224
Langue
anglais
Notes
Publication types: Journal Article ; Review Publication Status: ppublish
Résumé
Trabecular bone score (TBS) is a recently-developed analytical tool that performs novel grey-level texture measurements on lumbar spine dual X-ray absorptiometry (DXA) images, and thereby captures information relating to trabecular microarchitecture. In order for TBS to usefully add to bone mineral density (BMD) and clinical risk factors in osteoporosis risk stratification, it must be independently associated with fracture risk, readily obtainable, and ideally, present a risk which is amenable to osteoporosis treatment. This paper summarizes a review of the scientific literature performed by a Working Group of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis. Low TBS is consistently associated with an increase in both prevalent and incident fractures that is partly independent of both clinical risk factors and areal BMD (aBMD) at the lumbar spine and proximal femur. More recently, TBS has been shown to have predictive value for fracture independent of fracture probabilities using the FRAX® algorithm. Although TBS changes with osteoporosis treatment, the magnitude is less than that of aBMD of the spine, and it is not clear how change in TBS relates to fracture risk reduction. TBS may also have a role in the assessment of fracture risk in some causes of secondary osteoporosis (e.g., diabetes, hyperparathyroidism and glucocorticoid-induced osteoporosis). In conclusion, there is a role for TBS in fracture risk assessment in combination with both aBMD and FRAX.
Mots-clé
Absorptiometry, Photon, Adult, Aged, Algorithms, Bone Density, Bone and Bones/physiopathology, Bone and Bones/radiography, Cross-Sectional Studies, Cushing Syndrome/complications, Diabetes Mellitus, Type 2/complications, Female, Femur/pathology, Fracture Healing, Humans, Hyperparathyroidism, Primary/complications, Lumbar Vertebrae/pathology, Male, Middle Aged, Osteoarthritis/complications, Osteoporosis/diagnosis, Osteoporosis/physiopathology, Osteoporosis, Postmenopausal/diagnosis, Osteoporosis, Postmenopausal/physiopathology, Osteoporotic Fractures/diagnosis, Osteoporotic Fractures/physiopathology, Probability, Risk Assessment, Risk Factors
Pubmed
Web of science
Création de la notice
13/07/2015 9:22
Dernière modification de la notice
20/08/2019 16:30