PPAR gamma: an essential role in metabolic control.
Détails
ID Serval
serval:BIB_BBA12A0D8601
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
PPAR gamma: an essential role in metabolic control.
Périodique
Nutrition, Metabolism, and Cardiovascular Diseases
ISSN
0939-4753 (Print)
ISSN-L
0939-4753
Statut éditorial
Publié
Date de publication
2001
Volume
11
Numéro
1
Pages
64-69
Langue
anglais
Résumé
The peroxisome proliferator-activated receptor gamma is a nuclear hormone receptor playing a crucial role in adipogenesis and insulin sensitization. Prostaglandin J2 derivatives and the antidiabetic thiazolidinediones are its respective natural and synthetic ligands. The RXR/PPAR gamma heterodimer has also been reported to have important immunomodulatory activities and its pleiotropic functions suggest wide-ranging medical implications.
Mots-clé
Adipose Tissue/metabolism, Animals, Arteriosclerosis/etiology, Gene Expression, Humans, Inflammation/etiology, Insulin/physiology, Ligands, Prostaglandin D2/analogs & derivatives, Prostaglandin D2/analysis, Receptors, Cytoplasmic and Nuclear/genetics, Receptors, Cytoplasmic and Nuclear/metabolism, Thiazoles, Thiazolidinediones, Transcription Factors/genetics, Transcription Factors/metabolism
Pubmed
Web of science
Création de la notice
07/03/2013 16:07
Dernière modification de la notice
20/08/2019 15:29
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