Hormonal pleiotropy and the juvenile hormone regulation of Drosophila development and life history.

Détails

ID Serval
serval:BIB_BB3CE31199C7
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Hormonal pleiotropy and the juvenile hormone regulation of Drosophila development and life history.
Périodique
BioEssays
Auteur(s)
Flatt T., Tu M.P., Tatar M.
ISSN
0265-9247 (Print)
ISSN-L
0265-9247
Statut éditorial
Publié
Date de publication
2005
Peer-reviewed
Oui
Volume
27
Numéro
10
Pages
999-1010
Langue
anglais
Résumé
Understanding how traits are integrated at the organismal level remains a fundamental problem at the interface of developmental and evolutionary biology. Hormones, regulatory signaling molecules that coordinate multiple developmental and physiological processes, are major determinants underlying phenotypic integration. The probably best example for this is the lipid-like juvenile hormone (JH) in insects. Here we review the manifold effects of JH, the most versatile animal hormone, with an emphasis on the fruit fly Drosophila melanogaster, an organism amenable to both genetics and endocrinology. JH affects a remarkable number of processes and traits in Drosophila development and life history, including metamorphosis, behavior, reproduction, diapause, stress resistance and aging. While many molecular details underlying JH signaling remain unknown, we argue that studying "hormonal pleiotropy" offers intriguing insights into phenotypic integration and the mechanisms underlying life history evolution. In particular, we illustrate the role of JH as a key mediator of life history trade-offs.
Mots-clé
Aging/physiology, Animals, Behavior, Animal/physiology, Biological Evolution, Drosophila melanogaster/growth & development, Drosophila melanogaster/physiology, Hormones/metabolism, Insulin/metabolism, Juvenile Hormones/metabolism, Metamorphosis, Biological, Neurosecretory Systems/anatomy & histology, Neurosecretory Systems/physiology, Phenotype, Reproduction/physiology, Signal Transduction/physiology
Pubmed
Web of science
Création de la notice
28/01/2013 13:26
Dernière modification de la notice
20/08/2019 15:29
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