Hormonal pleiotropy and the juvenile hormone regulation of Drosophila development and life history.

Details

Serval ID
serval:BIB_BB3CE31199C7
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Hormonal pleiotropy and the juvenile hormone regulation of Drosophila development and life history.
Journal
BioEssays
Author(s)
Flatt T., Tu M.P., Tatar M.
ISSN
0265-9247 (Print)
ISSN-L
0265-9247
Publication state
Published
Issued date
2005
Peer-reviewed
Oui
Volume
27
Number
10
Pages
999-1010
Language
english
Abstract
Understanding how traits are integrated at the organismal level remains a fundamental problem at the interface of developmental and evolutionary biology. Hormones, regulatory signaling molecules that coordinate multiple developmental and physiological processes, are major determinants underlying phenotypic integration. The probably best example for this is the lipid-like juvenile hormone (JH) in insects. Here we review the manifold effects of JH, the most versatile animal hormone, with an emphasis on the fruit fly Drosophila melanogaster, an organism amenable to both genetics and endocrinology. JH affects a remarkable number of processes and traits in Drosophila development and life history, including metamorphosis, behavior, reproduction, diapause, stress resistance and aging. While many molecular details underlying JH signaling remain unknown, we argue that studying "hormonal pleiotropy" offers intriguing insights into phenotypic integration and the mechanisms underlying life history evolution. In particular, we illustrate the role of JH as a key mediator of life history trade-offs.
Keywords
Aging/physiology, Animals, Behavior, Animal/physiology, Biological Evolution, Drosophila melanogaster/growth & development, Drosophila melanogaster/physiology, Hormones/metabolism, Insulin/metabolism, Juvenile Hormones/metabolism, Metamorphosis, Biological, Neurosecretory Systems/anatomy & histology, Neurosecretory Systems/physiology, Phenotype, Reproduction/physiology, Signal Transduction/physiology
Pubmed
Web of science
Create date
28/01/2013 13:26
Last modification date
20/08/2019 15:29
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