Th2 responses predominate during the early phases of infection in patients with localized cutaneous leishmaniasis and precede the development of Th1 responses.
Détails
ID Serval
serval:BIB_BAB06A9E1569
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Th2 responses predominate during the early phases of infection in patients with localized cutaneous leishmaniasis and precede the development of Th1 responses.
Périodique
Infection and Immunity
ISSN
0019-9567 (Print)
ISSN-L
0019-9567
Statut éditorial
Publié
Date de publication
2003
Volume
71
Numéro
4
Pages
2244-2246
Langue
anglais
Résumé
Intralesional Th2 responses preceded the development of Th1 responses in localized cutaneous leishmaniasis due to Leishmania guyanensis. Although the number of parasites increased in Th2 lesions, no correlation was found between the levels of cytokine expression and the number of parasites. In contrast, the decreased number of parasites in Th1 lesions is negatively correlated to gamma interferon expression.
Mots-clé
Animals, Biopsy, Cytokines/biosynthesis, Humans, Leishmania/immunology, Leishmaniasis, Cutaneous/immunology, Leishmaniasis, Cutaneous/physiopathology, Skin/immunology, Skin/pathology, Th1 Cells/immunology, Th2 Cells/immunology
Pubmed
Web of science
Open Access
Oui
Création de la notice
25/10/2011 14:10
Dernière modification de la notice
20/08/2019 15:28
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