SLE-Associated Defects Promote Altered T Cell Function.
Détails
ID Serval
serval:BIB_B94359FDEE6B
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
SLE-Associated Defects Promote Altered T Cell Function.
Périodique
Critical reviews in immunology
ISSN
1040-8401 (Print)
ISSN-L
1040-8401
Statut éditorial
Publié
Date de publication
2017
Peer-reviewed
Oui
Volume
37
Numéro
1
Pages
39-58
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
Publication Status: ppublish
Publication Status: ppublish
Résumé
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease linked to profound defects in the function and phenotype of T lymphocytes. Here, we describe abnormal signaling pathways that have been documented in T cells from patients with SLE and discuss how they impact gene expression and immune function, in order to understand how they contribute to disease development and progression.
Mots-clé
Animals, Humans, Lupus Erythematosus, Systemic/immunology, Lymphocyte Activation/immunology, Phenotype, Signal Transduction/immunology, T-Lymphocytes/immunology
Pubmed
Web of science
Création de la notice
15/02/2018 20:10
Dernière modification de la notice
20/08/2019 15:27
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