Production of antibody to hepatitis A virus and hepatitis B surface antigen measured after combined hepatitis A/hepatitis B vaccination in 242 adult volunteers

Détails

ID Serval
serval:BIB_B5FDCFC5499D
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Production of antibody to hepatitis A virus and hepatitis B surface antigen measured after combined hepatitis A/hepatitis B vaccination in 242 adult volunteers
Périodique
Journal of Viral Hepatitis
Auteur(s)
Reutter  J., Bart  P. A., Francioli  P., Safary  A., Frei  P. C.
ISSN
1352-0504 (Print)
Statut éditorial
Publié
Date de publication
05/1998
Volume
5
Numéro
3
Pages
205-11
Notes
Clinical Trial
Controlled Clinical Trial
Journal Article --- Old month value: May
Résumé
Two batches of a new hepatitis A/hepatitis B combined vaccine were tested in 242 healthy students. Three injections, given at 0, 1 and 6 months, produced seroconversion rates and hepatitis A virus (HAV) and hepatitis B surface antigen (HBsAg) antibody levels comparable to those reported after administration of separate monocomponent vaccines. The vaccine proved to be safe and well-tolerated. Influence of host factors, such as elevated body mass index or gender, were investigated and proven to be of little influence on the immunoresponse.
Mots-clé
Adult Female Hepatitis A Antibodies Hepatitis A Vaccines Hepatitis A Virus, Human/*immunology Hepatitis Antibodies/*immunology Hepatitis B Antibodies/*immunology Hepatitis B Surface Antigens/*immunology Hepatitis B Vaccines/*immunology Humans Male Vaccination Vaccines, Combined/*immunology Vaccines, Synthetic/*immunology Viral Hepatitis Vaccines/*immunology
Pubmed
Web of science
Création de la notice
25/01/2008 18:07
Dernière modification de la notice
20/08/2019 16:24
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