Production of antibody to hepatitis A virus and hepatitis B surface antigen measured after combined hepatitis A/hepatitis B vaccination in 242 adult volunteers
Details
Serval ID
serval:BIB_B5FDCFC5499D
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Production of antibody to hepatitis A virus and hepatitis B surface antigen measured after combined hepatitis A/hepatitis B vaccination in 242 adult volunteers
Journal
Journal of Viral Hepatitis
ISSN
1352-0504 (Print)
Publication state
Published
Issued date
05/1998
Volume
5
Number
3
Pages
205-11
Notes
Clinical Trial
Controlled Clinical Trial
Journal Article --- Old month value: May
Controlled Clinical Trial
Journal Article --- Old month value: May
Abstract
Two batches of a new hepatitis A/hepatitis B combined vaccine were tested in 242 healthy students. Three injections, given at 0, 1 and 6 months, produced seroconversion rates and hepatitis A virus (HAV) and hepatitis B surface antigen (HBsAg) antibody levels comparable to those reported after administration of separate monocomponent vaccines. The vaccine proved to be safe and well-tolerated. Influence of host factors, such as elevated body mass index or gender, were investigated and proven to be of little influence on the immunoresponse.
Keywords
Adult
Female
Hepatitis A Antibodies
Hepatitis A Vaccines
Hepatitis A Virus, Human/*immunology
Hepatitis Antibodies/*immunology
Hepatitis B Antibodies/*immunology
Hepatitis B Surface Antigens/*immunology
Hepatitis B Vaccines/*immunology
Humans
Male
Vaccination
Vaccines, Combined/*immunology
Vaccines, Synthetic/*immunology
Viral Hepatitis Vaccines/*immunology
Pubmed
Web of science
Create date
25/01/2008 17:07
Last modification date
20/08/2019 15:24