Host genetics of invasive Aspergillus and Candida infections.

Détails

Ressource 1Demande d'une copie Sous embargo indéterminé.
Etat: Public
Version: Final published version
ID Serval
serval:BIB_B4D8A17056DF
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Host genetics of invasive Aspergillus and Candida infections.
Périodique
Seminars in Immunopathology
Auteur(s)
Wójtowicz A., Bochud P.Y.
ISSN
1863-2300 (Electronic)
ISSN-L
1863-2297
Statut éditorial
Publié
Date de publication
2015
Peer-reviewed
Oui
Volume
37
Numéro
2
Pages
173-186
Langue
anglais
Notes
Publication types: Journal Article Publication Status: ppublish Document type : review
Résumé
Invasive candidiasis and aspergillosis are major complications in surgical and onco-hematological patients, and still associated with an important morbidity and mortality. A large number of studies highlighted the potential role of host genetic polymorphisms that may influence susceptibility to fungal pathogens, but many were limited by insufficient statistical power, problematic design, and/or lack of replication. However, some relevant polymorphisms are now emerging from well-conducted studies whose associations have been replicated and/or are supported by strong biological evidence. Such polymorphisms together with other biomarkers may play a role in the prediction, diagnosis, and management of severe fungal infections in high-risk patients in the coming years.
Pubmed
Web of science
Création de la notice
13/03/2015 18:20
Dernière modification de la notice
20/08/2019 15:23
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