Secondary myelodysplastic syndromes following treatment with azathioprine are associated with aberrations of chromosome 7.

Détails

ID Serval
serval:BIB_AC57CA72EBF5
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Secondary myelodysplastic syndromes following treatment with azathioprine are associated with aberrations of chromosome 7.
Périodique
Haematologica
Auteur⸱e⸱s
Knipp S., Hildebrandt B., Richter J., Haas R., Germing U., Gattermann N.
ISSN
1592-8721 (Electronic)
ISSN-L
0390-6078
Statut éditorial
Publié
Date de publication
05/2005
Peer-reviewed
Oui
Volume
90
Numéro
5
Pages
691-693
Langue
anglais
Notes
Publication types: Letter ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Résumé
We report 14 cases of secondary myelodysplastic syndromes (sMDS) following treatment with azathioprine for non-malignant disorders. Long-term treatment with azathioprine seems to be associated with an increased risk of MDS and subsequent leukemic transformation.
Mots-clé
Adult, Aged, Aged, 80 and over, Autoimmune Diseases/drug therapy, Azathioprine/adverse effects, Azathioprine/therapeutic use, Cell Transformation, Neoplastic/chemically induced, Chromosomes, Human, Pair 7/ultrastructure, Female, Heart Transplantation, Humans, Immunosuppressive Agents/adverse effects, Immunosuppressive Agents/therapeutic use, In Situ Hybridization, Fluorescence, Kidney Transplantation, Male, Middle Aged, Monosomy, Myelodysplastic Syndromes/chemically induced, Myelodysplastic Syndromes/genetics, Postoperative Complications/chemically induced, Retrospective Studies, Rheumatic Diseases/drug therapy, Translocation, Genetic
Pubmed
Web of science
Création de la notice
16/07/2019 12:37
Dernière modification de la notice
21/08/2019 5:37
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