Nouvelle lumière sur la thérapie photodynamique cutanée [New light on skin photodynamic therapy]

Détails

ID Serval
serval:BIB_AB83BF8E543D
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Nouvelle lumière sur la thérapie photodynamique cutanée [New light on skin photodynamic therapy]
Périodique
Revue medicale suisse
Auteur⸱e⸱s
Kuonen F., Gaide O.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Statut éditorial
Publié
Date de publication
02/04/2014
Volume
10
Numéro
424
Pages
754,756-759
Langue
français
Notes
Publication types: English Abstract ; Journal Article ; Review
Publication Status: ppublish
Résumé
Photodynamic therapy (PDT) relies on the cellular toxicity of an exogenous porphyrin that is activated by light rays. Its specificity depends on its cellular uptake, which is typically high in cells with a high metabolism, such as cancer cells and several microbial pathogens. Both the diffusion of the substrate and the penetration of the light in the tissue limit its efficiency to the first few millimeters of the skin. This explains why this technique is used for the treatment of superficial skin cancers (actinic keratosis and basal cell carcinomas), but also for selected skin inflammatory diseases (psoriasis) or infections (leishmaniosis). However, at the bedside, the limitations of PDT are rather the complexity and the pain associated with the treatment. Herein, we present the new developments, in particular concerning the new light sources, which make PDT a better option for our patients.

Mots-clé
Humans, Light, Photochemotherapy/adverse effects, Photochemotherapy/trends, Photochemotherapy/utilization, Professional Practice/standards, Protoporphyrins/administration & dosage, Skin Diseases/drug therapy
Pubmed
Création de la notice
02/11/2017 12:05
Dernière modification de la notice
20/08/2019 15:15
Données d'usage