Evaluation of the susceptibility of pathogenic Candida species to fluconazole. Fluconazole Global Susceptibility Study Group.

Détails

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Version: Final published version
Licence: Non spécifiée
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ID Serval
serval:BIB_A442E9CC8FFB
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Evaluation of the susceptibility of pathogenic Candida species to fluconazole. Fluconazole Global Susceptibility Study Group.
Périodique
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
Auteur⸱e⸱s
Bille J., Glauser M.P.
ISSN
0934-9723
Statut éditorial
Publié
Date de publication
1997
Peer-reviewed
Oui
Volume
16
Numéro
12
Pages
924-8
Langue
anglais
Notes
Publication types: Journal Article - Publication Status: ppublish
Résumé
A fluconazole 25 microg disk diffusion test was used to test 2230 consecutively isolated Candida strains from 42 different hospital laboratories in 23 countries. Ninety seven percent of 1634 Candida albicans isolates and 83.4% of 596 non-Candida albicans isolates were susceptible to fluconazole, applying the proposed breakpoints (> or = 26 mm for susceptible strains and 18-25 mm for dose-dependent susceptible strains). This is the first hospital laboratory study to evaluate a large number and wide range of sequential Candida isolates from patients with all types of hospital infections. The fluconazole disk diffusion test appears to be a low-cost, reproducible, and accurate means of assessing the in vitro susceptibility of Candida isolates.
Mots-clé
Antifungal Agents, Candida albicans, Candidiasis, Dose-Response Relationship, Drug, Drug Resistance, Microbial, Evaluation Studies as Topic, Fluconazole, Humans, Microbial Sensitivity Tests, Time Factors
Pubmed
Web of science
Open Access
Oui
Création de la notice
11/02/2008 12:39
Dernière modification de la notice
14/02/2022 7:56
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