Evaluation of the susceptibility of pathogenic Candida species to fluconazole. Fluconazole Global Susceptibility Study Group.

Details

Ressource 1Download: serval:BIB_A442E9CC8FFB.P001 (453.76 [Ko])
State: Public
Version: author
License: Not specified
It was possible to publish this article open access thanks to a Swiss National Licence with the publisher.
Serval ID
serval:BIB_A442E9CC8FFB
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Evaluation of the susceptibility of pathogenic Candida species to fluconazole. Fluconazole Global Susceptibility Study Group.
Journal
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
Author(s)
Bille J., Glauser M.P.
ISSN
0934-9723
Publication state
Published
Issued date
1997
Peer-reviewed
Oui
Volume
16
Number
12
Pages
924-8
Language
english
Notes
Publication types: Journal Article - Publication Status: ppublish
Abstract
A fluconazole 25 microg disk diffusion test was used to test 2230 consecutively isolated Candida strains from 42 different hospital laboratories in 23 countries. Ninety seven percent of 1634 Candida albicans isolates and 83.4% of 596 non-Candida albicans isolates were susceptible to fluconazole, applying the proposed breakpoints (> or = 26 mm for susceptible strains and 18-25 mm for dose-dependent susceptible strains). This is the first hospital laboratory study to evaluate a large number and wide range of sequential Candida isolates from patients with all types of hospital infections. The fluconazole disk diffusion test appears to be a low-cost, reproducible, and accurate means of assessing the in vitro susceptibility of Candida isolates.
Keywords
Antifungal Agents, Candida albicans, Candidiasis, Dose-Response Relationship, Drug, Drug Resistance, Microbial, Evaluation Studies as Topic, Fluconazole, Humans, Microbial Sensitivity Tests, Time Factors
Pubmed
Web of science
Open Access
Yes
Create date
11/02/2008 12:39
Last modification date
01/10/2019 6:19
Usage data