The fight of viruses against apoptosis.

Détails

ID Serval
serval:BIB_A1E4DA0EFEBD
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
The fight of viruses against apoptosis.
Périodique
Current Opinion in Genetics and Development
Auteur⸱e⸱s
Tschopp J., Thome M., Hofmann K., Meinl E.
ISSN
0959-437X[print], 0959-437X[linking]
Statut éditorial
Publié
Date de publication
1998
Volume
8
Numéro
1
Pages
82-87
Langue
anglais
Résumé
The induction of apoptosis of virus-infected cells is an important host defense mechanism against invading pathogens. Some viruses express anti-apoptotic proteins that efficiently block apoptosis induced by death receptors or in response to stress signaled through mitochondria. Viral interference with host cell apoptosis leads to enhanced viral replication and may promote cancer.
Mots-clé
Animals, Apoptosis, CASP8 and FADD-Like Apoptosis Regulating Protein, Carrier Proteins/metabolism, Cysteine Proteinase Inhibitors/metabolism, Humans, Intracellular Signaling Peptides and Proteins, Mitochondria/metabolism, Proto-Oncogene Proteins c-bcl-2/metabolism, Viral Proteins/metabolism, Virus Physiological Phenomena
Pubmed
Web of science
Création de la notice
24/01/2008 16:19
Dernière modification de la notice
20/08/2019 16:07
Données d'usage