The fight of viruses against apoptosis.
Details
Serval ID
serval:BIB_A1E4DA0EFEBD
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
The fight of viruses against apoptosis.
Journal
Current Opinion in Genetics and Development
ISSN
0959-437X[print], 0959-437X[linking]
Publication state
Published
Issued date
1998
Volume
8
Number
1
Pages
82-87
Language
english
Abstract
The induction of apoptosis of virus-infected cells is an important host defense mechanism against invading pathogens. Some viruses express anti-apoptotic proteins that efficiently block apoptosis induced by death receptors or in response to stress signaled through mitochondria. Viral interference with host cell apoptosis leads to enhanced viral replication and may promote cancer.
Keywords
Animals, Apoptosis, CASP8 and FADD-Like Apoptosis Regulating Protein, Carrier Proteins/metabolism, Cysteine Proteinase Inhibitors/metabolism, Humans, Intracellular Signaling Peptides and Proteins, Mitochondria/metabolism, Proto-Oncogene Proteins c-bcl-2/metabolism, Viral Proteins/metabolism, Virus Physiological Phenomena
Pubmed
Web of science
Create date
24/01/2008 16:19
Last modification date
20/08/2019 16:07
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