Historical Hallmarks of Anticoagulation and Antiplatelet Agents.

Détails

ID Serval
serval:BIB_9FEA766E28BF
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Historical Hallmarks of Anticoagulation and Antiplatelet Agents.
Périodique
Current Pharmaceutical Design
Auteur(s)
Tsoucalas G., Chevallier J., Karamanou M., Papaioannou T., Sgantzos M., Androutsos G.
ISSN
1873-4286 (Electronic)
ISSN-L
1381-6128
Statut éditorial
Publié
Date de publication
2016
Peer-reviewed
Oui
Volume
22
Numéro
13
Pages
1857-1861
Langue
anglais
Notes
Publication types: Journal ArticlePublication Status: ppublish
Résumé
Thrombosis is a well known phenomenon among physicians since antiquity. A variety of peculiar agents, such as leeches and bark, were used to prevent it. Hirudin was used during the 19th century. The next eon, heparin, strepokinase, urokinase, TPA, dicumarol, warfarin, aspirin, ticlopidine, Clopidogrel, SSHA and SP54 provoked huge advances in anticoagulation. During 21st century with the use of fondaparinux, dabigatran, rivaroxaban and Ticagrelor antithrombotic prevention and therapeutic interaction entered an era of medical challenges. Although the risk after a thrombotic episode is now highly reduced, blood clots still present damaging or even lethal consequences in human organisms and further research is strongly recommended.
Pubmed
Web of science
Création de la notice
01/05/2016 16:58
Dernière modification de la notice
20/08/2019 15:06
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