Historical Hallmarks of Anticoagulation and Antiplatelet Agents.

Details

Serval ID
serval:BIB_9FEA766E28BF
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Historical Hallmarks of Anticoagulation and Antiplatelet Agents.
Journal
Current Pharmaceutical Design
Author(s)
Tsoucalas G., Chevallier J., Karamanou M., Papaioannou T., Sgantzos M., Androutsos G.
ISSN
1873-4286 (Electronic)
ISSN-L
1381-6128
Publication state
Published
Issued date
2016
Peer-reviewed
Oui
Volume
22
Number
13
Pages
1857-1861
Language
english
Notes
Publication types: Journal ArticlePublication Status: ppublish
Abstract
Thrombosis is a well known phenomenon among physicians since antiquity. A variety of peculiar agents, such as leeches and bark, were used to prevent it. Hirudin was used during the 19th century. The next eon, heparin, strepokinase, urokinase, TPA, dicumarol, warfarin, aspirin, ticlopidine, Clopidogrel, SSHA and SP54 provoked huge advances in anticoagulation. During 21st century with the use of fondaparinux, dabigatran, rivaroxaban and Ticagrelor antithrombotic prevention and therapeutic interaction entered an era of medical challenges. Although the risk after a thrombotic episode is now highly reduced, blood clots still present damaging or even lethal consequences in human organisms and further research is strongly recommended.
Pubmed
Web of science
Create date
01/05/2016 16:58
Last modification date
20/08/2019 15:06
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