Mechanistic insight into the function of the microbiome in lung diseases.

Détails

ID Serval
serval:BIB_9D6D50B43F33
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Mechanistic insight into the function of the microbiome in lung diseases.
Périodique
The European respiratory journal
Auteur(s)
Ubags NDJ, Marsland B.J.
ISSN
1399-3003 (Electronic)
ISSN-L
0903-1936
Statut éditorial
Publié
Date de publication
09/2017
Peer-reviewed
Oui
Volume
50
Numéro
3
Pages
1-12
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: epublish
Résumé
The lung harbours a diverse array of microbes whose dynamic composition is influenced by both host and environmental factors. Thus far, most studies have described the microbial composition of healthy or diseased lungs and provided an overview of the differences between topographical locations within the respiratory tract. However, insight into the functional mechanisms underlying host-microbe interactions and how they might drive lung health and disease are limited. This review provides an overview of the current mechanistic understanding of the microbiome, crosstalk between tissue compartments, and its involvement in respiratory diseases.
Mots-clé
Host-Pathogen Interactions, Humans, Lung/microbiology, Lung Diseases/immunology, Lung Diseases/microbiology, Lung Diseases/physiopathology, Microbiota
Pubmed
Web of science
Création de la notice
25/09/2017 13:37
Dernière modification de la notice
20/08/2019 15:03
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