Mechanistic insight into the function of the microbiome in lung diseases.

Details

Serval ID
serval:BIB_9D6D50B43F33
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Mechanistic insight into the function of the microbiome in lung diseases.
Journal
The European respiratory journal
Author(s)
Ubags NDJ, Marsland B.J.
ISSN
1399-3003 (Electronic)
ISSN-L
0903-1936
Publication state
Published
Issued date
09/2017
Peer-reviewed
Oui
Volume
50
Number
3
Pages
1-12
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: epublish
Abstract
The lung harbours a diverse array of microbes whose dynamic composition is influenced by both host and environmental factors. Thus far, most studies have described the microbial composition of healthy or diseased lungs and provided an overview of the differences between topographical locations within the respiratory tract. However, insight into the functional mechanisms underlying host-microbe interactions and how they might drive lung health and disease are limited. This review provides an overview of the current mechanistic understanding of the microbiome, crosstalk between tissue compartments, and its involvement in respiratory diseases.
Keywords
Host-Pathogen Interactions, Humans, Lung/microbiology, Lung Diseases/immunology, Lung Diseases/microbiology, Lung Diseases/physiopathology, Microbiota
Pubmed
Web of science
Create date
25/09/2017 14:37
Last modification date
20/08/2019 16:03
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